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Biohybrid centimeter-scale robots developed from optoelectronics and optogenetic muscles can be controlled wirelessly. 

Haptic interfaces can be used to add sensations of touch to virtual and augmented reality experiences. Soft, flexible devices that deliver spatiotemporal patterns of touch across the body, potentially with full-body coverage, are of particular interest for a range of applications in medicine, sports and gaming. Here we report a wireless haptic interface of this type, with the ability to display vibro-tactile patterns across large areas of the skin in single units or through a wirelessly coordinated collection of them. The lightweight and flexible designs of these systems incorporate arrays of vibro-haptic actuators at a density of 0.73 actuators per square centimetre, which exceeds the two-point discrimination threshold for mechanical sensation on the skin across nearly all the regions of the body except the hands and face. A range of vibrant sensations and information content can be passed to mechanoreceptors in the skin via time-dependent patterns and amplitudes of actuation controlled through the pressure-sensitive touchscreens of smart devices, in real-time with negligible latency. We show that this technology can be used to convey navigation instructions, to translate musical tracks into tactile patterns and to support sensory replacement feedback for the control of robotic prosthetics. 

Objective and Impact Statement . Real-time monitoring of the temperatures of regional tissue microenvironments can serve as the diagnostic basis for treating various health conditions and diseases. Introduction . Traditional thermal sensors allow measurements at surfaces or at near-surface regions of the skin or of certain body cavities. Evaluations at depth require implanted devices connected to external readout electronics via physical interfaces that lead to risks for infection and movement constraints for the patient. Also, surgical extraction procedures after a period of need can introduce additional risks and costs. Methods . Here, we report a wireless, bioresorbable class of temperature sensor that exploits multilayer photonic cavities, for continuous optical measurements of regional, deep-tissue microenvironments over a timeframe of interest followed by complete clearance via natural body processes. Results . The designs decouple the influence of detection angle from temperature on the reflection spectra, to enable high accuracy in sensing, as supported by in vitro experiments and optical simulations. Studies with devices implanted into subcutaneous tissues of both awake, freely moving and asleep animal models illustrate the applicability of this technology for in vivo measurements. Conclusion . The results demonstrate the use of bioresorbable materials in advanced photonic structures with unique capabilities in tracking of thermal signatures of tissue microenvironments, with potential relevance to human healthcare.